Pernicious anemia. From past to present. Pernicious anemia is currently the most common cause of vitamin B12 deficiency in Western countries. The histological lesion upon which this condition is based is autoimmune chronic atrophic gastritis. The destruction of parietal cells causes a deficiency in intrinsic factor, an essential protein for vitamin B12 absorption in the terminal ileum.
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Table S1: Amino acid changes to the HexA α-subunit to ... S1: Amino acid changes to the HexA...
Agen Stimulan Eritropoiesis ASE adalah medikasi yang memicu sumsum tulang agar membuat sel darah merah. Efek samping yang umum meliputi sakit sendi , ruam , muntah , dan sakit kepala. ASE pertama kali disetujui penggunaan kesehatannya di Amerika Serikat pada ASE mempertahankan hemoglobin pada level terendah yang meminimalisasi transfusi dan memenuhi kebutuhan seseorang sebaik mungkin. Tidak ada bukti bahwa satu senyawa lebih baik daripada yang lain dalam kondisi GGK. ASE bisa jadi gagal mencapai respons terapi yang cukup jika satu atau lebih kondisi berikut ada: .
Anemia Defisiensi Besi