FISIOPATOLOGIA DE DREPANOCITOSIS PDF

Asma en la infancia. Madrid: Elsiever; Asthma and sickle cell disease: two distinct diseases or part of the same process. Blake K, Lima J. Asthma in sickle cell disease: implications for treatment. Airway hyperresponsiveness and acute chest syndrome in children with sickle cell anemia.

Author:Mezishura Kazralar
Country:Martinique
Language:English (Spanish)
Genre:Love
Published (Last):3 June 2017
Pages:314
PDF File Size:7.91 Mb
ePub File Size:12.27 Mb
ISBN:330-1-57752-613-3
Downloads:37038
Price:Free* [*Free Regsitration Required]
Uploader:Baktilar



The pathophysiology of sickle cell disease: from the genetic mutation to multiorgan disfunction. The most important pathophysiological abnormalities of sickle cell disease are reviewed, taking into account three levels: a molecules and cells, b tissues, c organism as a whole. We dedicated especial attention to the chronic inflammatory phenomena, abnormally expressed adhesion molecules, the interaction among sickle cells, endothelial cells, leukocytes and platelets, and their role in the pathophysiology of vaso-occlusion.

The clinical manifestations, like anemia, pain crises and multiorgan dysfunction are covered. Factors that modulate disease severity, like the co-inheritance of a-thalassemia, gene mutations related to thrombophilia and the elevation of fetal hemoglobin are discussed. Key words: Sickle cell disease; pathophysiology; inflammation; adhesion molecules.

A idade mediana de morte de um grupo de 3. Telen MJ. Red blood cell surface adhesion molecules: their possible roles in normal human physiology and disease. Seminars in Hematology. Hebbel RP. Adhesive interactions of sickle cell erythrocytes with endothelium. The American Society for Clinical Investigation.

Okpala I. The intriguing contribution of withe blood cells to sickle cell disease - a red cell disorder. Blood Reviews. Modulation of endothelial cell activation in sickle cell disease: a pilot study.

Effects of hydroxyurea on the membrane of erythrocytes and platelets in sickle cell anemia. Decrease of very late activation antigen-4 and CD36 on reticulocytes in sickle cell patients treated with hydroxyurea. Plasma endothelin-1, cytokine, and prostaglandin E 2 levels in sickle cell disease and acute vaso-oclusive sickle crisis. Cell-cell interactions: leucocyte-endothelial interactions. Current Opinion in Hematology.

Causes and outcomes of the acute chest syndrome in sickle cell disease. N Engl J Med. Total hip arthroplasty in sickle cell hemoglobinopathies. J Am Acad Orthop Surg. Acute chest syndrome in sickle cell disease: clinical presentation and course.

Cooperative Study of Sickle Cell Disease. Mortality in sickle cell disease: life expectancy and risk factors for early death. Genetic control of F cells in human adults.

Bantu beta s cluster haplotype predominates among Brazilian blacks. Am J Phys Anthropol. The heterogeneity of the beta s cluster haplotypes in Brazil. Gene Geogr. Beta S-gene-cluster haplotypes in sickle cell anemia patients from two regions of Brazil. Am J Hematol. Sickle cell disease in a Brazilian population from Sao Paulo: a study of the beta s haplotypes. Hum Hered. Effect of alpha-thalassemia and beta-globin gene cluster haplotypes on the hematological and clinical features of sickle-cell anemia in Brazil.

Atypical beta s haplotypes are generated by diverse genetic mechanisms. Braz J Med Biol Res. Clinical, hematological, and molecular characterization of sickle cell anemia pediatric patients from two different cities in Brazil.

Cad Saude Publica. Am J Hum Biol. Arterial ischemic stroke in childhood: the role of plasma-phase risk factors. Curr Opin Neurol. Association of the GA myeloperoxidase polymorphism with infection in sickle cell anemia.

O tema apresentado e o convite ao s autor es constam da pauta elaborada pelo co-editor, prof. All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License. Services on Demand Journal. ABSTRACT The most important pathophysiological abnormalities of sickle cell disease are reviewed, taking into account three levels: a molecules and cells, b tissues, c organism as a whole.

How to cite this article.

KEB INVERTER F4 MANUAL PDF

2013, NĂºmero 3

.

DESIGN THOMAS HAUFFE PDF

.

ASM ON EMC 5 3 PDF

.

CUERPOS Y ALMAS MAXENCE VAN DER MEERSCH PDF

.

Related Articles