Fructooligosaccharides FOS are sugars found naturally at high concentrations in the storage roots of yacon. This study was designed to analyze the beneficial effects of subchronic oral consumption of yacon root flour as a diet supplement in Streptozotocin-induced diabetic Wistar rats. Yacon flour is a natural product obtained by a simple process of dehydration of yacon roots without added preservatives or chemicals. The administration of FOS-rich yacon flour to diabetic rats for 90days did not significantly alter the body weight of animals throughout the experimental period. Interestingly, a significant decrease in fasting plasma triacylglycerol and very low-density lipoprotein levels were observed. In addition, the treatment was able to protect the diabetic rats of the postprandial peak of plasma triacylglycerol.

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We examined the beneficial effects and tolerance of yacon syrup on human health. Methods: Obese and slightly dyslipidemic pre-menopausal women were studied over a day period in a double-blind placebo-controlled experiment. We used two doses of yacon syrup, 0. At the start and end of the study, anthropometric measurements, blood glucose, calcium, lipid and insulin concentrations and Homeostasis Model Assessment index were determined.

Results: The recommended daily consumption of yacon syrup with no undesirable gastrointestinal effects is 0. Daily intake of yacon syrup produced a significant decrease in body weight, waist circumference and body mass index. Additionally, decrease in fasting serum insulin and Homeostasis Model Assessment index was observed.

The consumption of yacon syrup increased defecation frequency and satiety sensation. Fasting glucose and serum lipids were not affected by syrup treatment and the only positive effect was found in serum LDL-cholesterol levels.

Conclusions: Yacon syrup is a good source of fructooligosaccharides and its long-term consumption produced beneficial health effects on obese pre-menopausal women with insulin resistance. This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable.

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Full-text links Cite Favorites. Yan MR, et al. Effect of yacon Smallanthus sonchifolius on colonic transit time in healthy volunteers. Geyer M, et al. Epub Sep Yacon syrup: Food applications and impact on satiety in healthy volunteers. Gomes da Silva MF, et al. Food Res Int. Epub Jul PMID: Machado AM, et al. Epub Dec Caetano BF, et al. Show more similar articles See all similar articles.

Kim B, et al. J Obes Metab Syndr. Epub Nov Choquechambi LA, et al. Rao M, et al. J Diabetes Res. Chen H, et al. Show more "Cited by" articles See all "Cited by" articles. Publication types Randomized Controlled Trial Actions. Research Support, Non-U. Gov't Actions. MeSH terms Adult Actions. Anthropometry Actions. Body Mass Index Actions. Dose-Response Relationship, Drug Actions. Double-Blind Method Actions. Female Actions. Humans Actions. Middle Aged Actions. Substances Blood Glucose Actions.

Insulin Actions. Lipids Actions. Plant Extracts Actions. Plant Preparations Actions. Calcium Actions. Full-text links [x] Elsevier Science. Copy Download.


Yacon Syrup: Beneficial Effects on Obesity and Insulin Resistance in Humans

Smallanthus sonchifolius yacon , a native plant of South America, was observed to improve lipid profile in rodents and humans. This study aimed to investigate the antiobesity properties of yacon roots in a high-fat-diet HFD model and the underlying mechanisms. HFD Y and HFD Y rats exhibited marked attenuation of weight gain, a decrease in visceral fat pad weight, a restoration of the serum lipid profile and atherogenic index in a dose-dependent manner, being the higher dose more effective. In addition, we found that HFD Y rats showed lower glucose and insulin levels, improved glucose tolerance, and insulin sensitivity. In the second approach, we determined that yacon supplementation potentiates the effects of the HFD reversion to a standard diet.


Yacon tuberous root Smallanthus sonchifolius : cultivation potentialities, technological and nutritional aspects. E-mail: isabellesantana yahoo. Yacon Smallanthus sonchifolius is a plant that belongs to Asteraceae family, originated from Andean regions. The tubers contain high water content, reduced energetic value and, unlikely most tuberous species which store the carbohydrates in the form of starch, yacon has fructooligosaccharides FOS as its main reserve carbohydrate, being highlighted by its bifidogenic activity.

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